Pharmacology and Molecular Medicine PhD Program

Our mission is to train the next generation of scientists and leaders in the field of Pharmacology and Molecular Medicine.

Students receive expert training from nationally and internationally renowned Program faculty to interrogate the molecular mechanisms of biological systems and disease and to leverage discoveries for therapeutic intervention in the areas of neuroscience, cancer biology, signal transduction, structural biology, cardiovascular biology, precision medicine, and computational biology. Graduates have been highly successful in academic, biotechnology, and government careers.

 


Faculty and Student Achievements


Student Eric Stokes Published

Eric Stokes - Stokes EG, Kim H, Ko J, Aoto J. A systematic structure-function characterization of a human mutation in Neurexin-3α reveals an extracellular modulatory sequence that stabilizes neuroligin-1 binding to enhance the postsynaptic properties of excitatory synapses. J Neurosci. 2024 Sep 4:e1847232024. doi: 10.1523/JNEUROSCI.1847-23.2024. Epub ahead of print. PMID: 39231636.

Stokes Publication

 

 

Student Dillon Boulton Published

Dillon Boulton - Boulton DP, Caino MC. Emerging roles for Mitochondrial Rho GTPases in tumor biology. J Biol Chem. 2024 Aug 14;300(9):107670. doi: 10.1016/j.jbc.2024.107670. Epub ahead of print. PMID: 39128718.

Boulton Publication

 

 

Student Nicole Brown's Review Published

Mach 21, 2024 - Congratulations to current student Carolyn Nicole Brown for review publication, Studying CaMKII: Tools and standards.

Brown Publication

 

 

Studying CaMKII: Tools and standards

Pharmacology Student Tyler Martinez Published in eNeuro

February 8, 2024 - Congratulations to current student Tyler Martinez for his publication in eNeuro, Amyloid-β-Induced Dendritic Spine Elimination Requires Ca2+-Permeable AMPA Receptors, AKAP-Calcineurin-NFAT Signaling, and the NFAT Target Gene Mdm2.

Martinez Publication

 

 

Amyloid-β-Induced Dendritic Spine Elimination Requires Ca2+-Permeable AMPA Receptors, AKAP-Calcineurin-NFAT Signaling, and the NFAT Target Gene Mdm2

Pharmacology Student Brian Brady Published in Nature Chemical Biology

January 12, 2024 - Congratulations to current student Brian Brady for his publication in Nature Chemical Biology, A Platform to Induce and Mature Biomolecular Condensates Using Chemicals and Light.

Brady Publication

 

 

Brady Journal Article 2023

 

Espinosa Awarded Anschutz Acceleration Initiative Grant

January 12, 2024 - Dr. Joaquin Espinosa and team are working to pave the way for the first immunomodulatory therapy for children with Down syndrome. Assuming positive results, their work could launch a new age of therapeutic development to improve the quality of life and extend the lifespan of millions of individuals affected by this chromosomal abnormality.

Joaquin Espinosa

Pharmacology Student Ian Shelton Published in Cancer Discovery

September 6, 2023 - Congratulations to current student Ian Shelton for his publication in Cancer Discovery, A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy.

Shelton Publication

 

 

Shelton Journal Article 2023

Pharmacology Program Students and Faculty Published in Nature

August 30, 2023 - Congratulations to current student Nicole Brown, alumnus Jonathan Tullis, and program faculty, Drs Ulli Bayer, Mark Dell’Acqua and Jason Aoto for their publication in Nature, LTP induction by structural rather than enzymatic functions of CaMKII.

Nature Publication

 

 

LTP induction by structural rather than enzymatic functions of CaMKII

Danielle Jeffrey receives F31 Award

August 24, 2023 - Congratulations to graduate student Danielle Jeffrey for receiving an F31 Award! Individual Predoctoral Fellowship (F31) Award supports promising doctoral candidates performing dissertation research and training in a scientific health-related field.

Danielle Jeffrey

Alumnus Brian Lloyd, PhD published in Nature Communications!

August 5, 2023 - Pharmacology PhD program alumnus Bryan Lloyd, PhD recently published his research Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus in Nature Communications.

LLoyd Publication


 

Bryan Lloyd Article Screenshot

Alumnus Jacqueline Turner, PhD published in Nature Communications

June 3, 2023 - Congratulations to alumnus Jacqueline Turner, PhD for their publication in Nature Communications!

Lysophosphatidic acid modulates CD8 T cell immunosurveillance and metabolism to impair anti-tumor immunity | Published Online June 3, 2023

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Jacqueline Turner Article Screenshot

Maddy Rodriguez receives NSF GRFP Fellowship

April 3, 2023 - Congratulations to Maddy Rodriguez on her GRFP Fellowship! Graduate Research Fellowship Program (GRFP) fellowships seek to broaden participation in science and engineering of underrepresented groups, including women, minorities, persons with disabilities, and veterans. The five-year fellowship provides three years of financial support inclusive of an annual stipend.

Madison Rodriguez

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