NATURE: Most people think about their genes as being uniquely identifiable to them. But new research by a team including Matthew DeCamp, MD, PhD and Marilyn Coors, PhD, shows that your " proteome "- the full set of proteins that are made from your genes, and include everything from blood cells to neurons to proteins like insulin - are just as unique.
They found that even with only a modest number of proteins, researchers can link people to their genome with remarkable accuracy - meaning the proteome is not as anonymous as once thought.
CU ANSCHUTZ NEWS: Matthew DeCamp, MD, PhD, and colleagues are shining a light on artificial intelligence’s role — and appearance — in health care. “Sometimes overlooked is what a chatbot looks like – its avatar,” the researchers write in a new paper published in Annals of Internal Medicine. “Current chatbot avatars vary from faceless health system logos to cartoon characters or human-like caricatures. Chatbots could one day be digitized versions of a patient’s physician, with that physician’s likeness and voice. Far from an innocuous design decision, chatbot avatars raise novel ethical questions about nudging and bias.”
NEWS NATION: The Indiana Medical Licensing Board voted to reprimand Dr. Caitlin Bernard, an Indianapolis obstetrician-gynecologist, after she spoke to the press about providing an abortion to a 10-year-old rape victim from Ohio.
NewsNation host Dan Abrams says there’s “no way” anyone would be able to identify the patient based on the information disclosed by the doctor. Center Director Matthew Wynia, MD, MPH, weighed in stating, " This is an illustration that medical ethics and journalistic ethics worked in this case. What did not work in this case is political ethics."
CU ANSCHUTZ NEWS: Lisa Bero, PhD, Chief Scientist at CBH and Research Professor at the the Colorado School of Public Health, recently led a National Academies of Sciences, Engineering and Medicine committee to improve processes that the Environmental Protection Agency (EPA) uses to identify harm posed to humans and the environment following industrial chemical spills. “Harm is something that I think gets conflated with safety,” said Bero.
“Established levels for a chemical’s harm don’t necessarily mean that if you’re slightly outside that level, it’s safe. And it further depends on the data as well, which is always limited. For example, liver toxicity studies are often done acutely – high levels of exposure in a short period of time – rather than at lower levels over an extended period," Bero said.
THE MILBANK QUARTERLY: Daniel Goldberg, JD, PhDand co-authors find that medicalization defines behavioral and physiological responses to social phenomena as individual pathology and disease (often with elements of stigma and social control), which are in turn viewed as individual medical problems to be diagnosed, treated, and influenced by authorities within the field of medicine.
Medicalization has encroached into both population health science and public health, bringing with it a myopic focus on the role of the medical care delivery system in intervening upon individual acute medical and social needs. This leaves the root-cause social, economic, and political drivers of population health invisible, ignored, and undisturbed.
NEW YORK TIMES: For the past decade, the White House and Congress have relied on the National Academies of Sciences, Engineering and Medicine, a renowned advisory group, to help shape the federal response to the opioid crisis, by convening expert panels or delivering policy recommendations and reports. Yet officials with the National Academies have kept quiet about one thing: their decision to accept roughly $19 million in donations from members of the Sackler family, the owners of Purdue Pharma, the maker of the drug OxyContin that is notorious for fueling the opioid epidemic.
CBH Chief Scientist Lisa Bero, PhD, said the group’s longtime failure to disclose financial ties between committee members and industry placed the Academies in the “dark ages” of research integrity. Accepting millions of dollars from the Sackler family while advising the federal government on pain policy “would be considered a conflict of interest under almost any conflict-of-interest policy I’ve ever seen.”
CU ANSCHUTZ TODAY: Everybody can help fight the health misinformation epidemic by not falling for – and not sharing – fake news. Lisa Bero, PhD Chief Scientist at CBH offers six tactics for separating fact from fiction in medical studies.
ORGANIZATION FOR DEFENDING VICTIMS OF VIOLENCE: As the international community finds itself fractured by conflicts, economic instability, pandemics, and the looming climate emergency, children are the ones who prove to be the most vulnerable. Iranian journalist Kourosh Ziabari interviews Warren Binford, JD, Ed.M.,, W.H. Lea for Justice Endowed Chair in Pediatric Law, Ethics & Policy, and Director for Pediatric Law, Ethics & Policy at the Kempe Center, about the key challenges to children’s rights and the most viable strategies to respond to them. Read article>>
BILL OF HEALTH-HARVARD LAW: Daniel Goldberg, JD, PhD argues that the premise of harm reduction rests on the idea that the perfect ought not be the enemy of the good. We live in a non-ideal world and public health interventions must be designed and implemented with such imperfections in mind.
Utopian ideals are important insofar as they frame the state of play between our current world and the destinations that we are trying to reach. However, the map is not the territory; clinging too much to a plan even when real-world conditions frustrate the ideal journey may leave travelers lost in the wilderness.
THE NATION: After 3.5 years of litigation, the DOJ has released video footage depicting the force-feeding of Mohammad Salameh, detained at ADX Florence, a federal prison in Colorado that houses one of the most secretive units in the United States. Salameh reports that he was force-fed more than 200 times over the course of his eight hunger strikes. The newly-released videos and an accompanying feature depict two instances of medical treatment forced on Salameh: one rehydration by IV and one feeding by nasogastric tube.
Matthew Wynia, MD, MPH, Director of the Center for Bioethics and Humanities and Advisor to Physicians for Human Rightssays there is no doubt that the Bureau of Prisons violated medical ethics and international law in providing forced medical treatment to Salameh. The force-feeding was conducted in a manner far outside of medical norms, causing significant discomfort to Salameh and potentially endangering his life.
5280 MAGAZINE: Carey Candrian, PhD, associate professor at CU School of Medicine, photographed older Colorado women who are a part of the LGBTQ community for her exhibit, Eye to Eye: Portraits of Pride, Strength, Beauty, which was displayed at the Fulginiti from October 2022-July 2021. The show is now on display at the Bob Ragland Branch Library in Denver.
"As academics, we get pressured to publish literature and write books, and I’ve done those things. None of them have had an impact as much as these photographs. I spend a lot of time thinking about how different things would be if we disseminated data in a way that was more accessible and in a way that could actually lead to change. Art is a really great way to change culture. It’s harder to hate someone to their face.”
"Doing research requires a certain level of trust between the researcher and the participants. The bravery and courage these women have shown has been phenomenal. They’ve been trained to stay silent, and then having to say yes to their photos and stories being on display throughout the entire state is a level of courage that I think is only made possible through that trust."
LA TIMES: Authors Wendy Netter Epstein and Daniel Goldberg warn that a direct consequence of ending the U.S. Public Health Emergency will be that uninsured and undocumented people won’t be able to access care for COVID. This is a tragedy in its own right and is likely to expand racial health inequalities connected to COVID. It will also have broader impacts on the community and the economy as COVID will spread, workforce shortages will continue and burdens of long COVID will increase.
They suggest States work to enact social policies that are likely to reduce COVID-related inequalities, such as paid sick leave laws, universal basic income requirements and supplemental nutrition assistance programs.
JOURNAL OF CLINICAL ETHICS: Author Kristin Furfari, MD, finds medical decision making for unrepresented patients is fraught with challenges, given the significant vulnerability of patients who are unable to make their own preferences known. At the 2022 Clinical Ethics Unconference in Atlanta, ethicists from different states and diverse healthcare institutions met to address the challenge and brainstorm approaches.
Furfari and Unconference participants concluded that the involvement of ethics committees is essential to support a thoughtful, transparent process in which diverse perspectives are recognized. Additionally, proxy decision makers should undergo bias education and cultural awareness training to minimize the potential contribution of harmful bias or stereotyping in the decision-making process.
HEALTH AFFAIRS: Daniel Goldberg, JD, PhD, and co-authors illustrate how laws and policies mediate structural stigma through the example of substance use disorder stigma; to explore potential mechanisms linking structural stigma in law to negative health outcomes, and therefore to health inequities for populations that are already marginalized; and to recommend an approach for revision of laws and policies that can significantly reduce structural stigma for targeted communities.
NATIONAL PUBLIC RADIO: It's been five months since Roe v. Wade was overturned, and now 13 states have laws banning abortion with limited exceptions for medical emergencies. Doctors who violate these laws could face felony charges, prison time and the loss of their medical license. There have been no reported prosecutions of health care workers, but Center Director Matthew Wynia, MD,MPH, says charges against doctors will certainly come. "There will be individual doctors who will get - presumably, will end up in court. And then, you know, the question will arise - were they supported? Can they be supported?"
KUNC ALL THINGS CONSIDERED: “Ragtime: The Mind and Music of Scott Joplin,” was performed by Juilliard-trained musician and Harvard-trained psychiatrist Dr. Richard Kogan at the Anschutz Campus on November 17th. KUNC's Michael Lyle sat down with Kogan to discuss how he weaves music and medicine together, and how Joplin's compositions serve as a way to explore issues such as racism and discrimination. Listen to the 5m interview>>
THE INTERCEPT: “If someone has capacity — they’re legally competent to make their own medical decisions — you cannot force-feed them,” said Matthew Wynia, MD, MPH, one of the expert reviewers of a research report by the ACLU and PHR titled Behind Closed Doors: Abuse and Retaliation Against Hunger Strikers in U.S. Immigration Detention, which spotlights ICE’s orders for involuntary and punitive treatment, including force-feeding, forced hydration, forced urinary catheterization, and other involuntary and invasive medical procedures. Wynia continues, "doctors do not have a place to use their skills and knowledge to be agents of the state for purposes of law enforcement, or for purposes of maintaining control of the prison population, or to try and break the hunger strike.”
HEALTHAFFAIRS FOREFRONT Mika Hamer, PhD, MPH and co-authors published a commentary about policy tools for securing long-term access to outpatient treatment for COVID-19 among uninsured and underinsured populations. They note the COVID-19 safety net was rapidly woven in the wake of a frightening worldwide pandemic. As time has passed, this safety net is unraveling. It is time to start putting it back together for an enduring effect.
The Department of Medicine Rising Star Award recognizes outstanding early-career faculty members who exemplify the department’s core values of excellence in patient care, research, education and community service. The 2022 Rising Star awardees are: Maheen Z. Abidi, MD, FAST, Division of Infectious Diseases, Kimberley D. Bruce, PhD, Division of Endocrinology, Metabolism and Diabetes, Matthew DeCamp, MD, PhD, Division of General Internal Medicine and Center for Bioethics and Humanities, and Joseph Alan Hippensteel, MD, MS, Division of Pulmonary Sciences and Critical Care Medicine. Congratulations Dr. DeCamp!!
The El Pomar Foundation recently recognized Pete Coors, chairman of the Molson Coors Beverage Company, and Marilyn Coors, PhD, associate professor emerita at the Center for Bioethics and Humanities, with the 2022 Ben S. Wendelken Trustee Award.